INVESTIGATING THE ANTIOXIDANT PROPERTIES OF ROYAL JELLY AND VITAMIN C ON ENZYMES, HISTOMORPHOMETRIC AND LIVER CELLS APOPTOSIS IN MICE SUFFERING HEMOLYTIC ANEMIA

Investigating the Antioxidant Properties of Royal Jelly and Vitamin C on Enzymes, Histomorphometric and Liver Cells Apoptosis in Mice Suffering Hemolytic Anemia

Background & Objective: Hemolytic anemia induced by phenylhydrazine (PHZ) as a hemolytic composition can change the function and structure of liver.Therefore, the present study attempts to evaluate the protective effects of vitamin C and royal jelly co-administration against the oxidative damages and liver apoptosis induced by hemolytic anemia in a

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The dual role of CXCL9/SPP1 polarized tumor-associated macrophages in modulating anti-tumor immunity in hepatocellular carcinoma

IntroductionThe main challenge for cancer therapy lies in immuno-suppressive tumor micro-environment.Reprogramming tumor-associated macrophages (TAMs) into an anti-tumor phenotype is a promising strategy.MethodsA comprehensive analysis by combing multi-regional single-cell, bulk and spatial transcriptome profiling with radiomics characterization wa

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